Decreased MIR2911 absorption in human with SIDT1 polymorphism fails to inhibit SARS-CoV-2

(Nanjing University School of Life Sciences) In a new study in Cell Discovery, Liang Li and Chen-Yu Zhang's group at Nanjing University and two other groups report that SIDT1 polymorphism remarkably decreases HD-MIR2911 absorption in human. Exosome isolated from volunteers that carry SIDT1 polymorphism has lower level of HD-MIR2911 and fails to inhibit of SARS-CoV-2 replication.